A new CO2 inhalation system for studying regulation of breathing.
نویسندگان
چکیده
This paper describes the development of a computer-controlled system that controls inspired CO2 or end-tidal PCO2 (PETCO2) to follow preprogrammed functions such as step, sinusoid, and pulse, under normoxic, hyperoxic, and hypoxic conditions. The system uses a proportional-integral (PI) controller that was optimized by adjusting the PI parameters so as to minimize the integral-time of absolute error (ITAE) performance parameter.
منابع مشابه
Ventilatory responses to rebreathing and carbon dioxide inhalation during anaesthesia in children.
In 12 spontaneously breathing intubated children (9.3-25 kg), ventilatory responses to rebreathing and to the inhalation of carbon dioxide (CO2) were investigated during halothane anaesthesia for minor surgical procedures. A T-piece (Mapleson F system) was used, modified by the insertion of a pneumotachograph and a paediatric airway adaptor of an in-line capnograph in the patient limb. Exhaled ...
متن کاملEvaluation of the Droplet Collapsibility in Inhalation Drug Delivery through a 3D Computational Study
Background: Several multiphase flow analyses have been developed to predict the fate of particles used in inhalation drug delivery; however, the collapse of droplets during their passage through respiratory tract has not been investigated. Objective: To assess the probability of droplet collapse in the upper respiratory tract.Methods: A 3D model of mouth-to-second generation airway after the tr...
متن کاملChronic immobilization stress occludes in vivo cortical activation in an animal model of panic induced by carbon dioxide inhalation
Breathing high concentrations of carbon dioxide (CO2) can trigger panic and anxiety in humans. CO2 inhalation has been hypothesized to activate neural systems similar to those underlying fear learning, especially those involving the amygdala. Amygdala activity is also upregulated by stress. Recently, however, a separate pathway has been proposed for interoceptive panic and anxiety signals, as p...
متن کاملمقایسه روش های اینداکشن استنشاقی Single breath inhalation و Tidal volume technique با اینداکشن وریدی (نسدونال، ساکسینیل)، دانشگاه علوم پزشکی تهران، 1379
The induction characteristic of halothane in nitrous oxide and oxygen were compared with halothane in oxygen alone and intravenous induction with thiopentum and succinylcholine.Materials and Methods: A vital capacity technique was used for the gaseous induction groups using a mapleson F system and a 1-litre reservoir bag. four end points of anesthesia were recorded: time to cessation of hand gr...
متن کاملThe Effect of Intermittent Exposure to 3% C02 on Respiration
An investigation was conducted to determine whether intermittent exposure to 3% CO2 results in a saturation of the body with carbon dioxide and whether a compensation of the respiratory acidosis is induced by carbon dioxide inhalation. One healthy male subject was exposed for six days, 15 hours daily, to a CO2 concentration rising from 0 3% at normal oxygen concentrations of 20 21% O2. Average ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The Japanese journal of physiology
دوره 39 4 شماره
صفحات -
تاریخ انتشار 1989